Changes in the Electrical Properties of Supraoptic Nucleus Oxytocin and Vasopressin Neurons during Lactation
نویسندگان
چکیده
منابع مشابه
Changes in the electrical properties of supraoptic nucleus oxytocin and vasopressin neurons during lactation.
Magnocellular oxytocin (OT) and vasopressin (VP) neurons adopt different firing patterns in response to relevant physiological stimuli. OT neurons selectively display short (2-4 sec), high-frequency bursts of action potentials that are highly synchronized and correlated with OT release during lactation. The present experiments were done to determine whether the electrophysiological properties o...
متن کاملReorganization of the dendritic trees of oxytocin and vasopressin neurons of the rat supraoptic nucleus during lactation.
Oxytocin (OT) and vasopressin (VP) release from the neurohypophysis are correlated with the electrical activity of magnocellular cells (MNCs) in the supraoptic (SON) and paraventricular nuclei. Synaptic inputs to MNCs influence their electrical activity and, hence, hormone release. During lactation OT neurons display a synchronized high-frequency bursting activity preceding each milk ejection. ...
متن کاملVasopressin differentially modulates non-NMDA receptors in vasopressin and oxytocin neurons in the supraoptic nucleus.
Magnocellular neurons of the supraoptic nucleus release the neuropeptides oxytocin and vasopressin from their dendrites to regulate their synaptic inputs. This study aims to determine the cellular mechanism by which vasopressin modulates excitatory synaptic transmission. Presumably by electroporation through perforated patch, we were able to successfully introduce biocytin into cells in which w...
متن کاملThe vasopressin and oxytocin neurons in the human supraoptic and paraventricular nucleus; changes with aging and in senile dementia.
The neuropeptides vasopressin (AVP) and oxytocin (OXT) are supposed to be involved not only in peripheral functions (e.g. diuresis, labour and lactation) but also in central processes that are frequently disturbed during aging and senile dementia (e.g. fluid and electrolyte homeostasis and cognitive functions). A concomitant decrease in activity of the hypothalamo-neurohypophyseal system (HNS) ...
متن کاملCirculating secretin activates supraoptic nucleus oxytocin and vasopressin neurons via noradrenergic pathways in the rat.
Secretin is a 27-amino acid brain-gut peptide from duodenal S-cells. We tested the effects of systemic administration of secretin to simulate its postprandial release on neuroendocrine neurons of the supraoptic nucleus (SON) in urethane-anesthetized female rats. Secretin dose-dependently increased the firing rate of oxytocin neurons, more potently than cholecystokinin, and dose-dependently incr...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1996
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.16-16-04861.1996